2000 AD Slaine: Megrim

Going by the alias of Megrim, Medb cast a glamour over Ragall, manipulating him and allowing the Fomorians into Tír na nÓg. Slowly the land fell into despair and the men became weak. Thanks to Niamh, Ragall eventually broke free of his glamour and seeing the damage he had unwillingly caused, he abdicated and allowed himself to be put to death. With no other likely successor in line, Medb expected to become the new Queen. However, Sláine returned home just before the ceremony ended and he was made the new king.

Shortly afterwards during the 'Horned King' saga, 'Megrim' accompanied Sláine as he brought the tribes together. She tried several times to sabotage this, at one point summoning Avagddu to kill Niamh, and was later responsible for the death of The Knucker, Sláine's dragon. She was eventually discovered thanks to Ukko and fled back to her master until the final battle between Sláine and the Drune Lords and the combined tribes. By the climax of the war she was presumed dead after having been flung from her dragon.